`ExposoGraph.reference_data`¶

Curated gene panels and activity scores from the CarcinoGenomic Platform.

Gene Panel Data¶

ExposoGraph.reference_data.TIER1_GENES¶: List of 13 Tier 1 core carcinogen-metabolizing enzyme dictionaries.

ExposoGraph.reference_data.TIER2_GENES¶: List of 23 Tier 2 extended gene panel dictionaries.

ExposoGraph.reference_data.CURATION_SOURCE_MANIFEST¶: Structured curation-source manifest describing the manuscript-aligned primary sources and the implementation-level supporting sources used by ExposoGraph.

ExposoGraph.reference_data.REFERENCE_KEGG_PATHWAYS¶: Curated KEGG pathway catalog used to track the reference pathway context for carcinogen metabolism and DNA-damage interpretation.

ExposoGraph.reference_data.ACTIVITY_SCORES¶: Dictionary mapping gene IDs to lists of per-allele activity score entries. Each entry has allele, value, phenotype, and confidence keys.

ExposoGraph.reference_data.ACTIVITY_SCORE_METADATA¶: Dictionary mapping gene IDs to evidence metadata for each activity score table, including evidence_basis, note, and supporting references.

ExposoGraph.reference_data.build_tier1_panel()[source]¶

Return a KnowledgeGraph containing all 13 Tier 1 genes as Enzyme nodes.

ExposoGraph.reference_data.build_tier2_panel()[source]¶

Return a KnowledgeGraph containing all Tier 2 genes as Enzyme nodes.

ExposoGraph.reference_data.build_full_panel()[source]¶

Return a KnowledgeGraph with all Tier 1 + Tier 2 genes (36 total).

ExposoGraph.reference_data.get_activity_scores(gene)[source]¶

Look up activity score entries for a gene. Returns None if not found.

ExposoGraph.reference_data.get_activity_score_metadata(gene)[source]¶

Return evidence metadata for a gene’s activity score table.

ExposoGraph.reference_data.get_activity_score_references(gene)[source]¶

Return supporting references for a gene’s activity score table.